Renal Tubular Transport #15. S1 Segment, Proximal Tubule. Phosphate Transport 1

in hive-163521 •  4 months ago  (edited)

Picture Steemit Renal Tubular Transport.jpg

Here, we show the following in the apical membrane of the S1 segment of the proximal tubule.

  • The NaPi-IIa cotransporter, which brings 3 sodium ions with 1 HPO42-
  • The NaPi-IIc cotransporter, which brings 2 sodium ions with 1 HPO42- (not in S3 segment)
  • The PiT-2 cotransporter, which brings 2 sodium ions with 1 H2PO4-

The basolateral transporter of phosphate forms into the interstitial space is still unknown.

The same electrochemical gradient generated by the Na/K ATPase mentioned in the previous post serves as the force behind the sodium/phosphate cotransporter

Picture Steemit Tubular Cell Phosphate Transport 1.jpg

Bibliography
Biber,J, N. Hernando, I. Forster, H. Murer . “Regulation of Phosphate Transport in Proximal Tubules." European Journal of Physiology 408, No. 1 (2009): 39-52. https://doi.org/10.1007/s00424-008-0580-8.

Previous Posts in this Series
Renal Tubular Transport #1. S1 Segment, Proximal Tubule. Sodium Transport 1 (Sodium/Hydrogen Ion Transport) (2nd Edition)
Renal Tubular Transport #2. S1 Segment, Proximal Tubule. Sodium Transport 2 (Sodium/Phosphate Transport) (2nd Edition)
Renal Tubular Transport #3. S1 Segment, Proximal Tubule. Sodium Transport 3
Renal Tubular Transport #4. S1 Segment, Proximal Tubule. Sodium Transport 4
Renal Tubular Transport #5. S1 Segment, Proximal Tubule. Sodium Transport 5
Renal Tubular Transport #6. S1 Segment, Proximal Tubule. Sodium Transport 6
Renal Tubular Transport #7. S1 Segment, Proximal Tubule. Sodium Transport 7
Renal Tubular Transport #8. S1 Segment, Proximal Tubule. Sodium Transport 8
Renal Tubular Transport #9. S1 Segment, Proximal Tubule. Potassium Transport 1
Renal Tubular Transport #10. S1 Segment, Proximal Tubule. Potassium Transport 2
Renal Tubular Transport #11. S1 Segment, Proximal Tubule. Calcium Transport 1
Renal Tubular Transport #12. S1 Segment, Proximal Tubule. Water Transport 1
Renal Tubular Transport #13. S1 Segment, Proximal Tubule. Magnesium Transport 1
Renal Tubular Transport #14. S1 Segment, Proximal Tubule. Glucose Transport 1
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